PBEF1 Antilichaam - C-terminalgebied: HRP (ARP42255_T100-HRP)

Nicotinamide phosphoribosyltransferase

VF, PBEF, PBEF1, VISFATIN, 1110035O14Rik

10135

P43490

NP_005737

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human PBEF1

PBEF1 catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

UBC; NEDD8; NDRG1; CTSA; PEPD; MVD; GSR; ASS1; ANXA6; CD81; AKT2; ADORA2A; IFITM3; ND1; GGT1; FTL; CUL5; DDA1; GBAS; FANCA

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

54kDa

Chen, M.P., (2006) J. Clin. Endocrinol. Metab. 91 (1), 295-299

Wet Ice

491

NAMPT

NAMPT

Rabbit

Nicotinamide phosphoribosyltransferase

NM_005746

VTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEAAH