PBEF/visfatine/NAMPT-eiwit (His & GST-tag)

Nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme belonging to the family of glycosyltransferases, to be specific, the pentosyltransferases. This enzyme participates in nicotinate and nicotinamide metabolism. This enzyme catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1- pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. NAMPT is also considered as an essential enzyme mediating granulocyte colony-stimulating factor (G-CSF) -triggered granulopoiesis in healthy individuals and individuals with severe congenital neutropenia. Intracellular NAMPT and NAD+ amounts in myeloid cells, as well as plasma NAMPT and NAD+ levels, were increased by G-CSF treatment of both healthy volunteers and individuals with congenital neutropenia.

1110035O14Rik Protein; PBEF Protein; PBEF1 Protein; VF Protein; VISFATIN Protein

P43490

Human

Human

His-/GST-Tag

See Datasheet send with the product

< 1.0 EU per μg protein as determined by the LAL method.

≥ 90 % as determined by SDS-PAGE. ≥ 80 % as determined by SEC-HPLC.

Data not available

728

Lyophilized

20mM Tris, 500mM NaCl, pH 8.0, 20% gly, 0.3mM DTT

See Datasheet

75 kDa

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Insect cells