PBIT
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
The JARID1 (Jumonji AT-Rich Interactive Domain 1) family of lysine demethylases demethylates the trimethylated lysine 27 in histone H3 (H3K4me3) . PBIT is a potent and selective inhibitor of JARID1 (IC50 = 3, 4.9 and 6 μM for JARID1B, 1A and 1C, respectively) . Selective for JARID1 over UTX and JMJD3. Treatment of cells with PBIT inhibits the demethylation of H3K4me3. It inhibits proliferation of breast cancer cell lines expressing high levels of JARID1B1.
Unconjugated
Off-white solid
-20°C
Beschrijving
PBIT Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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