PBX1 Mouse Monoclonal Antibody [Kloon ID: UMLBI110]

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t (1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar

Carrier-free (BSA/glycerol-free) PBX1 mouse monoclonal antibody, clone UMLBI110

DKFZp686B09108; MGC126627

Homo sapiens PBX homeobox 1 (PBX1), transcript variant 1, mRNA.

5087

P40424

Unconjugated

IHC 1:100~200

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Stem cell - Pluripotency, Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

PBX1

https://www.ncbi.nlm.nih.gov/gene/?term=5087

https://www.uniprot.org/uniprot/P40424