PCDHB16 Antilichaam

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

57717

Q9NRJ7

Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 29-90 of human PCDHB16 (NP_066008.2) .

Unconjugated

Primary Antibodies

Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

Mouse brain

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 85kDa

IgG

WB: 1:200 - 1:2000

PCDHB16

Rat brain

Protocadherin beta 16

Homo sapiens

ME1, PCDH-BETA16, PCDH3X, PCDHB8a, protocadherin beta-16, cadherin ME1, protocadherin beta 8a, protocadherin-3x

WB

Liquid