
PCDHB6 Polyklonale Antilichaam, Cy5 Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain. Unlike most protocadherin-beta proteins, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, suggesting a role in signal transduction cascade events.
PCDH beta6;  PCDH beta 6; PCDHB 6; Protocadherin beta 6.
Cell membrane
• Rabbit
21-120/794
PCDHB6
• Polyclonal
• IgG
Cy5
KLH conjugated synthetic peptide derived from human PCDHB6
IF (IHC-P), IF (IHC-F), IF (ICC)
Purified by Protein A.
625,650nm/670nm
1µg/µl
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Human, Mouse, Rat, Cow, Sheep, Pig, Horse
Beschrijving
PCDHB6 Polyklonale Antilichaam, Cy5 Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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