PCNA Antilichaam

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

5111

P12004

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human PCNA (NP_002583.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Signal Transduction, Stem Cell

Affinity purification

U-251MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 36kDa

IgG

WB: 1:500 - 1:2000IHC: 1:50 - 1:100

PCNA

A-549

HL-60

HepG2

NIH/3T3

SW480

Proliferating cell nuclear antigen

Homo sapiens

PCNA, MGC8367

WB, IHC

Liquid