PCNA Mouse Monoclonal Antibody [Kloon ID: LBI4B2]

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) PCNA mouse monoclonal antibody, clone LBI4B2

ATLD2

Homo sapiens proliferating cell nuclear antigen (PCNA), transcript variant 1, mRNA.

5111

P12004

Unconjugated

Base excision repair, Cell cycle, DNA replication, Mismatch repair, Nucleotide excision repair

Base excision repair, Cell cycle, DNA replication, Mismatch repair, Nucleotide excision repair

WB 1:2000, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Stem cell - Pluripotency

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

PCNA

https://www.ncbi.nlm.nih.gov/gene/?term=5111

https://www.uniprot.org/uniprot/P12004