PCSK5 Antilichaam - middengebied HRP (ARP43530_P050-HRP)

Proprotein convertase subtilisin/kexin type 5

PC5, PC6, PC6A, SPC6

5125

Q92824

NP_006191

Human, Mouse, Rat, Cow, Dog, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human PCSK5

PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. PCSK5 mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

NOTCH2NL; KRTAP10-3; KRTAP10-8; KRTAP10-7; LCE3C; KRTAP4-12; NUFIP2; GLRX3; STK16; MEOX2; KRTAP5-9; env; Hoxa1; ATN1; UBC; CACNA1A; APPBP2; AMH; REN; PTPRM; PMCH; ITGA6

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

PCSK5 is strongly supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 100%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 79%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

89kDa

Szumska, D., (2008) Genes Dev. 22 (11), 1465-1477

Wet Ice

913

PCSK5

PCSK5

Rabbit

Proprotein convertase subtilisin/kexin type 5

NM_006200

CAGAGADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENGYKSCKKCDIS