PCSK9 Proteïne (C-His, Human)
Gecertificeerd

PCSK9 Proteïne (C-His, Human)

Catalog #: P527385
Maat: 100 µg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

Abbreviation

PCSK9

Synonyms

FH3, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9, PSEC0052

Host

• HEK 293

Tag

C-His

Endotoxin

< 0.5 EU per mg protein.

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized Recombinant Human LDL Receptor Protein (Fc Tag) (Cat: 10231-H05H) at 2 μg/mL (100 μL/well) can bind Recombinant Human PCSK9 / NARC1 (D374Y, V474I, G670E) Protein (His Tag) (Cat: 10594-H08H1-UE), the EC50 is 12-36 ng/mL (Routinely tested) . 2.Loaded Recombinant Human LDL Receptor Protein (Fc Tag) (Cat. No. 10231-H05H) on proA Biosensor, can bind Recombinant Human PCSK9 / NARC1 (D374Y, V474I, G670E) Protein (His Tag) (Cat. No. 10594-H08H1-UE) with an affinity constant of 2.04 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Function

Met 1-Gln 692

Molecular Weight

The recombinant human PCSK9 consists 673 amino acids and predicts a molecular mass of 72.6 kDa. Due to autocatalytic cleavage, non-covalently associated fragments appear as a major band at approximately 60–70 kDa and smaller fragments at 17–18 kDa on SDS-PAGE under reducing conditions.

Species

Human

Beschrijving

PCSK9 Proteïne (C-His, Human) Beschikbaar in 100 µg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamPCSK9 Proteïne (C-His, Human)
Categorie
Beschikbare grootte100 µg
CatalogusnummerP527385