![PD-1 Recombinant antilichaam [RMP1-14] (OAAV00446)](/_ipx/q_80/productPlaceholder.webp)
PD-1 Recombinant antilichaam [RMP1-14] (OAAV00446)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
V-set and transmembrane domain-containing protein 3.
Q68D85
Mouse
Armenian hamsters were immunized with recombinant mouse TIGIT tetramers by a combination of s.c. and food pad immunization and booster injections. Draining lymph nodes were fused with Sp2/0-Ag14 cells, selected in HAT (hypoxanthine/aminopterin/thymidine) medium and supernatants were screened for specificity by ELISA and flow cytometry using TIGIT-transfectants.
This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster format, for improved compatibility with existing reagents, assays and techniques.
• Recombinant Monoclonal
4D4
Recombinant Monoclonal Antibody
Purified
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
PBS with 0.02% Proclin 300.
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
IgG, kappa
4D4 specifically recognises TIGIT.
TIGIT
Rabbit
T-cell immunoreceptor with Ig and ITIM domains
TIGIT
Beschrijving
PD-1 Recombinant antilichaam [RMP1-14] (OAAV00446) Beschikbaar in 200 µg. Bestel eenvoudig online met snelle levering.
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