PD1 (PDCD1) Mouse Monoclonal Antibody [Kloon ID: UMLBI199]

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul

Carrier-free (BSA/glycerol-free) PD-1 (PDCD1) mouse monoclonal antibody, clone UMLBI199

CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2

Homo sapiens programmed cell death 1 (PDCD1), mRNA.

5133

Q15116

Unconjugated

Cell adhesion molecules (CAMs), T cell receptor signaling pathway

Cell adhesion molecules (CAMs), T cell receptor signaling pathway

IHC 1:1000, WB 1:500, IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

PDCD1

https://www.ncbi.nlm.nih.gov/gene/?term=5133

https://www.uniprot.org/uniprot/Q15116