PD128763
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
PD128763 is a selective poly (ADP-ribose) polymerase inhibitor. PD128763 results in an enhancement of Streptozotocin -induced cytotoxicity. PD128763 can be used in leukemia research[1][2].
129075-56-5
12352005
H302, H315, H319, H332, H335
PARP
Cell Cycle/DNA Damage; Epigenetics
Cancer
99.57
O=C1NCCC=2C1=CC=CC2C
C10H11NO
161.20
H302, H315, H319, H332, H335
[1]Sebolt-Leopold JS, et al. Enhancement of alkylating agent activity in vitro by PD 128763, a potent poly (ADP-ribose) synthetase inhibitor. Int J Radiat Oncol Biol Phys. 1992;22 (3) :619-21. |[2]Yau L, et al. Repression of phosphoenolpyruvate carboxykinase gene activity by insulin is blocked by 3-aminobenzamide but not by PD128763, a selective inhibitor of poly (ADP-ribose) polymerase. Eur J Biochem. 1998 Apr 1;253 (1) :91-100.
Room Temperature
Store at room temperature 3 years
http://file.medchemexpress.com/batch_PDF/HY-W041672/
Reference compound1
No Development Reported
Beschrijving
PD128763 is a selective poly (ADP-ribose) polymerase inhibitor. PD128763 results in an enhancement of Streptozotocin -induced cytotoxicity. PD128763 can be used
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