PDCD10 Antilichaam, KO gevalideerd

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

11235

Q9BUL8

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PDCD10 (NP_009148.2) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Apoptosis, Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

A-431

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 26kDa

IgG

PDCD10

HepG2

Jurkat

MCF7

Mouse thymus

Mouse brain

Programmed cell death protein 10

Homo sapiens

Programmed cell death protein 10, Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15, PDCD10, CCM3, TFAR15

WB, IF

Liquid