PDCD1LG2-eiwit (C-His, mens)

PDCD1LG2

B7-DC, B7DC, bA574F11.2, Btdc, CD273, PD-L2, PDCD1L2, PDL2

C-His

< 1.0 EU per μg of the protein as determined by the LAL method

≥ 98 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC.

1.Loaded Recombinant Human PD-1 Protein, hFc Tag (Cat. No. 10377-H02H) on ProA Biosensor, can bind Recombinant Human PD-L2 / B7-DC Protein, His Tag (Cat. No. 10292-H08H) with an affinity constant of 0.154 μM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 2.Recombinant Human B7-DC / PD-L2 / CD273 Protein (His Tag) (Cat: 10292-H08H) captured on CM5 chip via Anti-His antibody, can bind Recombinant Human PD1 / PDCD1 / CD279 Protein (Fc Tag) (Cat: 10377-H02H) with an affinity constant of 20.000 nM as determined in an SPR assay (Biacore 8K) (QC tested) .

Met1-Pro219

The recombinant human PD-L2 consists of 211 amino acids and predicts a molecular mass of 24 kDa. As a result of glycosylation, the apparent molecular mass of rh PD-L2 is approximately 40-45 kDa in SDS-PAGE under reducing conditions.

Human