PDE1C Antilichaam

This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.

5137

Q14123

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 435-634 of human PDE1C (NP_001177985.1) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 81kDa

IgG

WB: 1:500 - 1:2000

PDE1C

Mouse heart

Mouse brain

Mouse testis

Rat heart

Rat brain

Phosphodiesterase 1C, calmodulin-dependent 70kDa

Homo sapiens

PDE1A, HCAM1, HSPDE1A, MGC26303, Hcam3

WB

Liquid