PDE6D (NM 002601) Humaan Recombinant eiwit

This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants. [provided by RefSeq, Mar 2014]

Purified recombinant protein of Human phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

JBTS22; PDED

5147

O43924, Q6IB24

NM_002601

2q37.1

E. coli

N-GST and C-His

Progesterone-mediated oocyte maturation, Purine metabolism

Progesterone-mediated oocyte maturation, Purine metabolism

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

45.2 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

PDE6D

Human

NP_002592

https://www.ncbi.nlm.nih.gov/gene/5147

https://www.uniprot.org/uniprot/O43924

https://www.ncbi.nlm.nih.gov/nuccore/NM_002601

https://www.ncbi.nlm.nih.gov/nuccore/NP_002592