Pdgfc Antilichaam - N-terminaal gebied: Biotine (ARP61794 P050-Biotine)

Platelet derived growth factor C

PDGF-, SCDGF, PDGF-C, VEGF-E, AI647969, 1110064L01Rik

54635

Q8CI19

NP_064355

Human, Mouse, Rat, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Pdgfc

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

39kDa

Wet Ice

345

PDGFC

Pdgfc

Rabbit

Platelet-derived growth factor C

NM_019971

MLLLGLLLLTSALAGQRTGTRAESNLSSKLQLSSDKEQNGVQDPRHERVV