PDGFRalfa D842V Recombinant humaan actief eiwit Kinase

PDGFRalpha is a receptor tyrosine kinases that stimulate cell survival, proliferation and motility. Upon PDGF binding, the receptor dimerizes and undergoes a conformational change, which activates the kinase domain. PDGFRalpha D842V is a mutant of PDGFRalpha. PDGFRalpha D842V Recombinant Human Active Protein Kinase is a recombinant PDGFRalpha D842V protein that can be used to study PDGFRalpha D842V-related functions[1].

12352211

PDGFR

Protein Tyrosine Kinase/RTK

Cancer

[PDGFRalphaD842VRecombinantHumanActiveProteinKinase]

[1]Arts FA, et al. PDGFRB mutants found in patients with familial infantile myofibromatosis or overgrowth syndrome are oncogenic and sensitive to imatinib. Oncogene. 2016 Jun 23;35 (25) :3239-48.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-E70762/

Enzyme

No Development Reported