PDGFRalfa T674I Recombinant humaan actief eiwit Kinase
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
PDGFRalpha is a receptor tyrosine kinases that stimulate cell survival, proliferation and motility. Upon PDGF binding, the receptor dimerizes and undergoes a conformational change, which activates the kinase domain. PDGFRalpha T674I is a mutant of PDGFRalpha. PDGFRalpha T674I Recombinant Human Active Protein Kinase is a recombinant PDGFRalpha T674I protein that can be used to study PDGFRalpha T674I-related functions[1].
12352211
PDGFR
Protein Tyrosine Kinase/RTK
Cancer
[PDGFRalphaT674IRecombinantHumanActiveProteinKinase]
[1]Arts FA, et al. PDGFRB mutants found in patients with familial infantile myofibromatosis or overgrowth syndrome are oncogenic and sensitive to imatinib. Oncogene. 2016 Jun 23;35 (25) :3239-48.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-E70763/
Enzyme
No Development Reported
Beschrijving
PDGFRalpha is a receptor tyrosine kinases that stimulate cell survival, proliferation and motility. Upon PDGF binding, the receptor dimerizes and undergoes a co
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