PDK1 (Ab 241) Antilichaam

Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-ζ , RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development

5170

O15530

NP_002604.1

Human, Mouse, Rat

PDK1 (Ab-241) antibody was raised against a peptide sequence around aa.239~243 (A-N-S-F-V) derived from Human PDK1.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

63 kDa

This antibody detects endogenous level of total PDK1 protein.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

PDPK1

3-phosphoinositide dependent protein kinase-1

Homo sapiens

Scheid MP, et al. (2005) Mol Cell Biol; 25 (6) : 2347-63Chen H, et al. (2001) Biochemistry; 40 (39) : 11851-9Sato S, et al. (2002) J Biol Chem; 277 (42) : 39360-7Lim MA, et al. (2003) Proc Natl Acad Sci U S A; 100 (24) : 14006-11Beausoleil SA, et al. (2004) Proc Natl Acad Sci U S A; 101 (33) : 12130-5

PDK1, PDPK2, PRO0461, KIAA0288

WB, IHC, IF

4505695

Liquid