PDK1 Antilichaam

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.

5163

Q15118

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PDK1 (NP_002601.1) .

Unconjugated

Primary Antibodies

Cancer, Immunology, Signal Transduction

Affinity purification

LO2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 49kDa

IgG

WB: 1:500 - 1:1000

PDK1

NIH/3T3

Rat spleen

Pyruvate dehydrogenase kinase, isozyme 1

Homo sapiens

PDK1, PDHK1

WB

Liquid