PDK1 (fosfo Ser241) Antilichaam

Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-ζ , RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development.

5170

O15530

NP_002604.1

Human, Mouse, Rat

PDK1 (Phospho-Ser241) antibody was raised against a peptide sequence around phosphorylation site of serine 241 (A-N-S (p) -F-V) derived from Human PDK1.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

63 kDa

This antibody detects endogenous level of PDK1 only when phosphorylated at serine 241.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

PDPK1

3-phosphoinositide dependent protein kinase-1

Homo sapiens

Scheid MP, et al. (2005) Mol Cell Biol; 25 (6) : 2347-63Chen H, et al. (2001) Biochemistry; 40 (39) : 11851-9Sato S, et al. (2002) J Biol Chem; 277 (42) : 39360-7Lim MA, et al. (2003) Proc Natl Acad Sci U S A; 100 (24) : 14006-11

PDK1, PDPK2, PRO0461, NFKB3, PDPK1, PkB kinase, Protein kinase B kinase, hPDK1, kinase PDK1

WB, IHC, IF

4505695

Liquid