PDK3 Antilichaam - middengebied: FITC (ARP46126_P050-FITC)

Pyruvate dehydrogenase kinase, isozyme 3

CMTX6, GS1-358P8.4

5165

Q15120

NP_005382

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human PDK3

PDK3 belongs to the PDK/BCKDK protein kinase family. It contains 1 histidine kinase domain. PDK3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

APP; UBD; UBC; ICT1; EGFR; DLAT; PDHA1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

There is BioGPS gene expression data showing that PDK3 is expressed in OVCAR3

0.5 mg/ml

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 85%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

47kDa

Degenhardt, T., (2007) J. Mol. Biol. 372 (2), 341-355

Wet Ice

406

PDK3

PDK3

Rabbit

[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial

NM_005391

IYLKALSSESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKAK