PDX1 Mouse Monoclonal Antibody [Kloon ID: LBI2A12]

Pdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4) .

Carrier-free (BSA/glycerol-free) Pdx1 mouse monoclonal antibody, clone LBI2A12

GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1

Homo sapiens pancreatic and duodenal homeobox 1 (PDX1), mRNA.

3651

P52945

Unconjugated

Maturity onset diabetes of the young, Type II diabetes mellitus

Maturity onset diabetes of the young, Type II diabetes mellitus

WB 1:20000, IHC 1:50, IF 1:50~100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

PDX1

https://www.ncbi.nlm.nih.gov/gene/?term=3651

https://www.uniprot.org/uniprot/P52945