PE-Labeled Monoclonal Anti-Mens TIGIT Antibody, Rabbit IgG (M1G03) (0,03% Proclin)

T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is also known as V-set and immunoglobulin domain-containing protein 9 (VSIG9), V-set and transmembrane domain-containing protein 3 (VSTM3), which belongs to single-pass type I membrane protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM) . TIGIT is expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level) . TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Monoclonal Anti-Human TIGIT Antibody, Rabbit IgG (M1G03) is a rabbit monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which provides higher batch consistency and long term security of supply. It shows superior performance in flow cytometry assays with higher affinity and better specificity.

TIGIT

PE Labeled

Rabbit IgG | Rabbit Kappa

Flow Cytometry (Detection the expression of TIGIT on Human cells) .

Store at 2-8 °C for 12 months. Please protect from light and avoid repeated freeze-thaw cycles.

Liquid

PBS, pH7.4, 0.03% Proclin300, 0.2% BSA

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Blue ice

2-8°C, avoid light

50tests*4

HEK293

Rabbit

Trehalose