PEG10 Antilichaam - N-terminalgebied: HRP (ARP51313_P050-HRP)

Paternally expressed 10

EDR, HB-1, Mar2, RTL2, MEF3L, Mart2, RGAG3, SIRH1

23089

Q86TG7

NP_055883

Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N-terminal region of Human PEG10

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene.

SIAH1; FAM127C; LDOC1; CALCOCO2; FAM127A; UBC; MAPT; HNRNPUL1; HNRNPH1; BAG1; TGFBR2; TGFBR1; BMPR1B; BMPR1A; ACVRL1; ACVR2B; ACVR2A; ACVR1B; ACVR1; RNF2; ZNF512B; RNF181; HMGCS1; TOLLIP; IRF4; SIAH2

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

80kDa

Wet Ice

708

PEG10

PEG10

Rabbit

Retrotransposon-derived protein PEG10

NM_015068

SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREVAKRKIR