PEG3 Antilichaam - C-terminalgebied: FITC (ARP38756 P050-FITC)

Paternally expressed 3

PW1, ZNF904, ZSCAN24, ZKSCAN22

5178

Q9GZU2

NP_006201

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human PEG3

PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells.

PEG3; ALB; USP7; TRAF2; SIAH2; SIAH1; BRCA1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

PEG3 is strongly supported by BioGPS gene expression data to be expressed in A204

0.5 mg/ml

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

181kDa

Dowdy, S.C., et al., (2005) Gynecol. Oncol. 99 (1), 126-134

Wet Ice

1588

PEG3

PEG3

Rabbit

Paternally-expressed gene 3 protein

NM_006210

FGECSGYIERASTSTGGANQADEKYFKCDVCGQLFNDRLSLARHQNTHTG