Peptide 234CM (TFA)

Peptide 234CM TFA is a peptide containing isoleucine at position 3, corresponding to the sequence of a point mutation in p53 codon 234. Peptide 234CM TFA induces potent cytotoxic T cell (CTL) and antitumor immune responses against mutant p53[1].

12352209

MDM-2/p53

Apoptosis

Cancer

98.39

OC(C=C1)=CC=C1C[C@H](NC([C@@H](N)CCCCN)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CS)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CS)C(N[C@H](C(O)=O)CCSC)=O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F.[x]

C42H69N11O14S3.xC2HF3O2

1048.26 (free base)

[1]Gabrilovich, et al. "Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function." Clinical cancer research 5.10 (1999) : 2963-2970.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P10610A/

Peptides

No Development Reported