Perforine-antilichaam [CE2.10]

5551

P14222

Human, Mouse

Perforin (monoclonal CE2.10) antibody was raised against recombinant mouse perforin (aa. 98-534) .

CE2.10

Unconjugated

Primary Antibodies

Immunology

Perforin (monoclonal CE2.10) antibody was purified to ≥95% in SDS-PAGE.

Batch dependent

PBS containing 0.02% sodium azide

None

Blue Ice

Perforin antibody can be stored at 4˚ C, stable for one year.

IgG2a

Perforin antibody can be used for detection of horse Perforin by western blot. This product also recognizes human, mouse, rat, sheep, goat and monkey apoPerforin. Method: Cell extracts from the T cell clone B6.1 (2x106) were resolved by SDS-PAGE under reducing conditions, transferred to nitrocellulose and probed with the CE2.10 antibody at 1 μ g/mL. Proteins were visualized using a peroxidase-conjugated antibody to mouse IgG (SBA) and a chemiluminescence detection system.

Perforin 1 (pore forming protein)

Homo sapiens

Perforin and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade: P. Li, et al.; Cell 91, 479 (1997) .

Perforin: can't live with it-can't live without it:J.C. Reed; Cell 91, 559 (1997) .

Prevention of apoptosis by Bcl-2: release of Perforin from mitochondria blocked: J. Yang, et al.; Science 275, 1129 (1997) .

Apaf-1, a human protein homologous to C. elegans CED-4, participates in Perforin-dependent activation of caspase-3: H. Zou, et al.; Cell 90, 405 (1997) .

WB, IP

Liquid