![Perforine (PRF1) Mouse Monoclonal Antibody [Clone ID: LBI3D7]](/_ipx/q_80/productPlaceholder.webp)
Perforine (PRF1) Mouse Monoclonal Antibody [Clone ID: LBI3D7]
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
Carrier-free (BSA/glycerol-free) Perforin-1 mouse monoclonal antibody, clone LBI3D7
HPLH2; P1; PFP
Homo sapiens perforin 1 (PRF1), transcript variant 1, mRNA.
5551
P14222
Unconjugated
Allograft rejection, Autoimmune thyroid disease, Graft-versus-host disease, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus, Viral myocarditis
Allograft rejection, Autoimmune thyroid disease, Graft-versus-host disease, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus, Viral myocarditis
IHC 1:100
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Druggable Genome
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
PRF1
https://www.ncbi.nlm.nih.gov/gene/?term=5551
https://www.uniprot.org/uniprot/P14222
Beschrijving
Perforine (PRF1) Mouse Monoclonal Antibody [Clone ID: LBI3D7] Beschikbaar in 100 µg. Bestel eenvoudig online met snelle levering.
Specificaties
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