Periplanetasine-2

Periplanetasin-2 is an antifungal peptide that induces oxidative stress through the production of reactive oxygen species (ROS) and lipid peroxidation. Periplanetasin-2 can also induce apoptosis[1].

2055935-42-5

12352209

Apoptosis; Bacterial; Reactive Oxygen Species (ROS)

Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Infection

O=C(N1[C@@H](CCC1)C(N[C@@H](CS)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N2[C@@H](CCC2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CNC=N4)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC5=CC=C(C=C5)O)N

C84H134N22O17S

1756.16

[1]Yun J, et al. The antifungal activity of the peptide, periplanetasin-2, derived from American cockroach Periplaneta americana. Biochem J. 2017 Aug 22;474 (17) :3027-3043.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11116/

Peptides

No Development Reported