Petiline

Petiline is a steroidal alkaloid found in Petilium raddeanum, acting as a selective antagonist of M cholinergic receptors. Petiline exerts anticholinergic effects (e.g., reducing vagal influence on the heart) by competitively blocking M cholinergic receptors, and also has central excitatory, cardiotonic, and spasmolytic activities. Petiline is promising for research of cholinergic system-related diseases (e.g., arrhythmia, intestinal spasm) [1].

26989-18-4

12352211

MAChR

GPCR/G Protein; Neuronal Signaling

Neurological Disease

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C27H43NO2

413.64

[1]Mirzaev Y R. Pharmacologic Properties of Certain Steroidal Alkaloids of Varying Structure[J]. Chemistry of natural compounds, 2004, 40 (4) .

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N15736/

Natural Products

No Development Reported