PEX19 Antilichaam - C-terminalgebied : FITC (ARP61545 P050-FITC)

Peroxisomal biogenesis factor 19

PXF, HK33, PMP1, PMPI, PXMP1, PBD12A, D1S2223E

5824

P40855

NP_002848

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs) . Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

FKBP7; IL23A; PEX3; UBC; PPIB; PTPLAD1; VCP; PXMP4; SLC25A17; PEX16; PEX11B; ABCD3; PMP22; EGFR; Cdkn2a; Pxmp2; TMEM54; MFSD5; PEX26; GSKIP; F11R; KIFAP3; OIP5; EIF1B; PEX11A; STK3; SRPK1; PEX14; PEX13; SMAD2; IRF3; CDC25A; NUDCD2; DSTN; NUBP2; HSPB1; PEX

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

PEX19 is strongly supported by BioGPS gene expression data to be expressed in HCT15

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Rat: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

33kDa

Wet Ice

299

PEX19

PEX19

Rabbit

Peroxisomal biogenesis factor 19

NM_002857

AETPTDSETTQKARFEMVLDLMQQLQDLGHPPKELAGEMPPGLNFDLDAL