PEX3 (CT) Antilichaam

PEX3 Antibody: PEX3 is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, PEX3 is necessary for the import of peroxisomal membrane proteins in the peroxisomes. Thus within the cell, PEX3 is stabilized by PEX19 preventing PEX3 aggregation. Mutations in the PEX19-binding domain of PEX3 reduce the affinity for PEX19 and destabilize PEX3.

8504

P56589

P56589

Human, Mouse, Rat

9665

Unconjugated

Primary Antibodies

Signal Transduction

PEX3 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1203 – A549 Cell Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: monkey (100%), cow (100%)

PEX3 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

PEX3 antibody can be stored at 4 ˚ C for three months and -20 ˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

WB: 2 μ g/mL; IF: 20 μ g/mL. Antibody validated: Western Blot in human, mouse and rat samples; Immunofluorescence in human, mouse and rat samples. All other applications and species not yet tested.

Human PEX3 has 1 isoform, including isoform 1 (373aa, 42kD) . Mouse PEX3 has 1 isoform (372aa, 42kD) . Rat PEX3 has one isoform (372aa, 42kD) . 9665 can detect PEX3 in human, mouse and rat.

PEX3

Cat. No. 17-003 – A549 Cell Slide

Homo sapiens

Ghaedi et al. Mol Biol Cell. 2000; 11 (6) :2085-2102

Fang et al. J Cell Biol. 2004;164 (6) :863-875

Hattula et al. PloS One. 2014; 9 (7) :e103101

Schmidt et al. Traffic. 2012; 13 (9) :1244-1260

PEX3 Antibody: Peroxisomal biogenesis factor 3, Peroxin-3, Peroxisomal assembly protein PEX3

ELISA, WB, IF

3914303

Liquid