PF-04995274
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1331782-27-4
PF-4995274
C07212-5mg
5-HT Receptor
Neuronal Signaling
C1CN (CCC1COC2=NOC3=C2C (=CC=C3) OC4CCOC4) CC5 (CCOCC5) O
C23H32N2O6
PF-04995274 (PF-4995274) is a potent, high-affinity, orally active and partial agonist of serotonin 4 receptor (5-HT4R) with EC50 of 0.47 nM, 0.36 nM, 0.37 nM and 0.26 nM for human 5-HT4A/4B/4D/4E, respectively. As for rat 5-HT4S/4L/4E, the EC50 is 0.59 nM, 0.65 nM and 0.62 nM, respectively. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease.
3 years -20°C powder
Beschrijving
PF-04995274 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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