PF-06835919
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
PF-06835919 is a potent (IC50 = 10 nM KHK-C; 170 nM KHK-A) inhibitor of ketohexokinase (KHK), the first enzyme in the fructose metabolic cascade.1 It displayed high selectivity against other sugar kinases. PF-06835919 prevented hyperinsulinemia, hypertriglyceridemia, and hepatic steatosis in fructose-fed rats.2 The increased tumor proliferation effect of fructose in CaSki cells was inhibited by PF-06835919.3 An interesting new tool to study metabolic and fatty liver diseases.
Unconjugated
White solid
-20°C
Beschrijving
PF-06835919 Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
Hettich Centrifuge Rotanta 460R Refrigerated Large Volume
CEN0703
1 Each
X4RF Refrigerated Centrifuge
75009936
1 Each
Drug Stability Chamber
500-DSC102
1 Unit
Modular Incubator Chamber
MIC-101
1 Unit
CYP707A2 Antibody
GTR17947107
2 mg
SsDNA Assay Kit
12645ES60
100 Tests
Eco Alu MTP (HxD) 6x7=42 plates 35mm, 223x630x135mm
TE15336
1 Piece
Recent gezochte producten
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
X4RF Refrigerated Centrifuge
75009936
1 Each
Low Speed Refrigerated Centrifuge
LX104LSR
1 Unit
Low Speed Refrigerated Centrifuge
LX117LSR
1 Unit
Low Speed Refrigerated Centrifuge
LX124LSR
1 Unit
Blood Bank Refrigerator
LX4000BBR
1 Unit
Blood Bank Refrigerator
LX4002BBR
1 Unit
Blood Bank Refrigerator
LX4003BBR
1 Unit