PF-06952229
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1801333-55-0
UNII-1KKS7U3X86
TGF-beta/Smad
TGF-beta/Smad
C23H24ClFN4O3
PF-06952229 (UNII-1KKS7U3X86) is a selective, orally available inhibitor of the serine/threonine kinase TGF-β receptor 1 (TGF-β-R1) . It inhibits pSMAD2 in both tumor and immune cells, reducing TGF-β signalling and reversing EMT in vitro. It modulates the tumor immune microenvironment and shows antitumor activity in mouse models.
2 years -20°C liquid
Beschrijving
PF-06952229 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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