PF-543
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1415562-82-1
Sphingosine Kinase 1 Inhibitor II
C03752-5mg
PF-543 (Sphingosine Kinase 1 Inhibitor II) is a potent, selective, reversible and sphingosine-competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3.6 nM. PF-543 is >100-fold selectivity for SPHK1 over SPHK2. PF-543 is an effective potent inhibitor of sphingosine 1-phosphate (S1P) formation in whole blood with an IC50 of 26.7 nM. PF-543 induces apoptosis, necrosis, and autophagy.
Beschrijving
PF-543 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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