PF-543 HCl
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
PF-543 (1706522-79-3) is a potent (IC50 = 2.0 nM) and selective (>100-fold over SphK2) reversible inhibitor of sphingosine kinase-1 (SphK1) .1 It induced autophagy in head and neck squamous cell carcinoma cells.2 PF-543 mitigated pulmonary fibrosis via reducing lung epithelial cell mitochondrial DNA damage and monocyte recruitment.3 It also alleviated sepsis-induced lung injury in an acute ethanol intoxication model in mice.4 PF-543 inhibited cell cycle and tumor growth in a xenograft model of non-small cell lung cancer.5
Unconjugated
White solid
-20°C
Beschrijving
PF-543 HCl Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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