PGAM5 (CT) Peptide

PGAM5 Antibody: PGAM5 is a central mediator for programmed necrosis induced by TNF and may be a regulator of mitochondrial dynamics. It displays phosphatase activity for serine/threonine residues, dephosphorylates and activates MAP3K5 kinase. It has apparently no phosphoglycerate mutase activity and is a substrate for a KEAP1-dependent ubiquitin ligase complex. It is also contributes to the repression of NFE2L2-dependent gene expression

192111

Q96HS1

Q96HS1

Peptides

200 ug/mL

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Blue Ice

Store PGAM5 (CT) Peptide at -20˚ C, stable for one year.

PGAM5 (CT) Peptideis used for blocking the activity of thePGAM5 (CT) Antibody

PGAM family member 5, mitochondrial serine/threonine protein phosphatase

Homo sapiens

Lo S. et al. Exp. Cell Res. 2018; 314 (8) : 1789-1803

Takeda et al. PNAS 2009; 106 (30) : 12301-12305

Want et al. Cell 2012; 148 (1-2) ; 228-243

Serine/threonine-protein phosphatase PGAM5 mitochondrial, Bcl-XL-binding protein v68, Phosphoglycerate mutase family member 5

Blocking

Human

150417955

Liquid