PHB2 Antilichaam - C-terminalgebied: FITC (ARP48316_P050-FITC)

Prohibitin 2

BAP, REA, p22, hBAP, Bap37, BCAP37, PNAS-141

11331

Q99623

NP_009204

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human PHB2

PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity) . It functions as an estrogen receptor (ER) -selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.

HUWE1; IGF1R; HDAC1; ESR1; KIAA1244; NCOR1; SUMO2; STAU1; UBC; MDM2; ASB14; ASB17; SUZ12; EED; RNF2; UPF2; ADRB2; CDK2; env; VCAM1; TEAD3; ITGA4; ILF3; FN1; ATF2; C1QBP; AFP; UBL4A; EPAS1; FMNL1; PAXIP1; MDC1; MYOD1; MEF2A; FHL2; ECT2; BRCA1; AKT1; Htt; U

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB, IHC

Affinity Purified

PHB2 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

33kDa

Ross, J.A., (2008) J. Biol. Chem. 283 (8), 4699-4713

Wet Ice

299

PHB2

PHB2

Rabbit

Prohibitin-2

NM_007273

KLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK