Phenidon (Standaard)

Phenidone, an orally active dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), ameliorates rat paralysis in experimental autoimmune encephalomyelitis. Phenidone is a potent hypotensive agent in the spontaneously hypertensive rat[1][2]. Phenidone is used as a photographic developer[3].

92-43-3

12352005

COX; Lipoxygenase

Immunology/Inflammation; Metabolic Enzyme/Protease

Inflammation/Immunology; Cardiovascular Disease

O=C1NN(C2=CC=CC=C2)CC1

C9H10N2O

162.19

[1]Moon C, et al. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res. 2005;1035 (2) :206-210.|[2]Stern N, et al. The lipoxygenase inhibitor phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. Am J Hypertens. 1993;6 (1) :52-58.|[3]Petrakiev A, et al. Emission spectral analysis using photographic plates treated with a phenidone developer. Talanta. 1969;16 (12) :1583-1587.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W010144R/

Reference Standards