PHF1 Antilichaam - N-terminaal gebied: Biotine (ARP39588_P050-Biotine)

PHD finger protein 1

PCL1, PHF2, hPHF1, MTF2L2, TDRD19C

5252

O43189

NP_077084

Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human PHF1

PHF1 has significant sequence similarity with Drosophila Polycomblike. It contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.

ATXN7L1; BIRC7; VAC14; HSD17B14; RBPMS; CALCOCO2; PDLIM7; TFCP2; NAB2; TRIM23; SUZ12; EZH2; NEK6; TP53; SUMO1; HIC1; ELAVL1; UBC; RAD50; NCR1; EED; SMC1A; XRCC5; RBBP7; XRCC6; DHX9; HIST1H3J; HIST1H3G; HIST1H3I; HIST1H3E; HIST1H3C; HIST1H3A; HIST1H3F; HIS

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Rabbit: 86%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

62kDa

Hong, Z., (2008) Nucleic Acids Res. 36 (9), 2939-2947

Wet Ice

567

PHF1

PHF1

Rabbit

PHD finger protein 1

NM_024165

MAQPPRLSRSGASSLWDPASPAPTSGPRPRLWEGQDVLARWTDGLLYLGT