PHKG2 Mouse Monoclonal Antibody [Kloon ID: LBI1F9]

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Carrier-free (BSA/glycerol-free) PHKG2 mouse monoclonal antibody, clone LBI1F9

GSD9C

Homo sapiens phosphorylase kinase catalytic subunit gamma 2 (PHKG2), transcript variant 1, mRNA.

5261

P15735

Unconjugated

Calcium signaling pathway, Insulin signaling pathway

Calcium signaling pathway, Insulin signaling pathway

WB 1:1000, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Protein Kinase

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

PHKG2

https://www.ncbi.nlm.nih.gov/gene/?term=5261

https://www.uniprot.org/uniprot/P15735