Phospho-dishovelled 2 (Thr224) Polyklonale Antilichaam, PerCP-conjugated

Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity) .

Segment polarity protein dishevelled homolog DVL-2; Dishevelled-2; DSH homolog 2; DVL2

1856

O14641

Thr224

Cytoplasm

Human

Phospho-Dishevelled 2 (Thr224)

PerCP

KLH conjugated synthetic phosphopeptide derived from human DVL2 around the phosphorylation site of Thr224

WB, IF (IHC-P)

Purified by Protein A.

482nm/677nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

This antibody will recognize DVL3 when phosphorylated at Thr205

1856

Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken