Phosphodifield 2 (Ser143) Polyklonale Antilichaam, RBITC Vervoeging

Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity) .

Segment polarity protein dishevelled homolog DVL-2; Dishevelled-2; DSH homolog 2; DVL2

1856

Ser143

Cytoplasm, Cell membrane

Human

Phospho-Dishevelled 2 (Ser143)

RBITC

KLH conjugated synthetic phosphopeptide derived from human Dishevelled 2 around the phosphorylation site of Ser143

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

570nm/595nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

1856

Mouse, Rat, Zebrafish