PHT-427-d4
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
PHT-427-d4 is the deuterium labeled PHT-427. PHT-247 is an inhibitor of the pleckstrin homology (PH) domain of Akt, and it is also an inhibitor of PDPK1 with Kis of 2.7 μM and 5.2 μM and for Akt and PDPK1, respectively.
12352005
Akt; Apoptosis; Isotope-Labeled Compounds
Apoptosis; Others; PI3K/Akt/mTOR
Cancer
O=S(C1=C(C([2H])=C(C([2H])=C1[2H])CCCCCCCCCCCC)[2H])(NC2=NN=CS2)=O
C20H27D4N3O2S2
413.63
[1]Meuillet EJ, et al. Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor. Mol Cancer Ther. 2010 Mar;9 (3) :706-17.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W719359/
Isotope-Labeled Compounds
No Development Reported
Beschrijving
PHT-427-d4 is the deuterium labeled PHT-427. PHT-247 is an inhibitor of the pleckstrin homology (PH) domain of Akt, and it is also an inhibitor of PDPK1 with Ki
Specificaties
Recent bekeken producten
PEPTIC DIGEST OF ANIMAL TISSUE (MEAT PEPTONE)
P16-102-01
500 g
GelRed® Agarose LE
#41029-5G
1x 5 g
HT115 (DE3) Super Competent Cells
D1045S
10x 100 μL
HT115
ACC-130
10 Tubes
Rat Reticulon-4 receptor, RTN4R ELISA Kit
MBS9325746-01
48 Well
Starfish Genomic DNA
GSF-390
0.025 mg
NPM2
570475-01
50 µg
15-PGDH Inhibitor Screening Kit (Fluorometric)
K503-100
100 Assays
Recent gezochte producten
MS Solution sufficient for 400 Mini, 142 Midi, 33 Maxi
MS10
Each
MS pipette, variable vol µme 10~100 µL
MSP-100
1 Unit
MS 12-ch pipette, variable vol µme 20~200 µL
MSP-12X200
1 Unit
MS 12-ch pipette, variable vol µme 2~20 µL
MSP-12X20
1 Unit
MS Rocking anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRK-3001
1 Unit
MS Orbital Shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NOR-30
1 Unit
MS Reciprocal anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRC-3001
1 Unit
MS pipette, variable vol µme 1000~10000 µL
MSP-10000
1 Unit