PI 3 Kinase klasse 2A (PIK3C2A) Mouse Monoclonal Antibody [Kloon ID: LBI2C11]

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) PIK3C2A mouse monoclonal antibody, clone LBI2C11

CPK; PI3-K-C2 (ALPHA) ; PI3-K-C2A

Homo sapiens phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha (PIK3C2A), transcript variant 1, mRNA.

5286

O00443

Unconjugated

Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system

Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system

WB 1:2000, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

PIK3C2A

https://www.ncbi.nlm.nih.gov/gene/?term=5286

https://www.uniprot.org/uniprot/O00443