PI3K/AKT-IN-4
Gecertificeerd

PI3K/AKT-IN-4

Catalog #: TN8157-01
Maat: 10 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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BTW niet inbegrepen
Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Target

CDK, PI3K, Akt, Apoptosis, PARP

Related Pathways

Apoptosis, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Chromatin/Epigenetic, Cytoskeletal Signaling

Bioactivity

PI3K/AKT-IN-4 (compound 3), a diterpenoid extracted from the roots and rhizomes of Salvia castanea Dielsf., exhibits antitumor properties by inhibiting cell viability and proliferation (IC 50 =4.72 μM) and promoting apoptosis in Hep3B cells. This compound obstructs the G0/G1 phase of the cell cycle, triggers mitochondrial dysfunction, and induces oxidative stress. Moreover, PI3K/AKT-IN-4 combats hepatocellular carcinoma through the inhibition of the PI3K-Akt signaling pathway and by interacting with PARP1 and CDK2 targets.

Molecular Formula

C19H26O2

Molecular Weight

286.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Beschrijving

PI3K/AKT-IN-4 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamPI3K/AKT-IN-4
Categorie
Beschikbare grootte10 mg
CatalogusnummerTN8157-01