
PI3K/AKT-IN-4
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CDK, PI3K, Akt, Apoptosis, PARP
Apoptosis, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Chromatin/Epigenetic, Cytoskeletal Signaling
PI3K/AKT-IN-4 (compound 3), a diterpenoid extracted from the roots and rhizomes of Salvia castanea Dielsf., exhibits antitumor properties by inhibiting cell viability and proliferation (IC 50 =4.72 μM) and promoting apoptosis in Hep3B cells. This compound obstructs the G0/G1 phase of the cell cycle, triggers mitochondrial dysfunction, and induces oxidative stress. Moreover, PI3K/AKT-IN-4 combats hepatocellular carcinoma through the inhibition of the PI3K-Akt signaling pathway and by interacting with PARP1 and CDK2 targets.
C19H26O2
286.41
Ice Packs
-20°C
Beschrijving
PI3K/AKT-IN-4 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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